Running head: B12 MALABSORPTION IN erstwhile(a) ADULTS: THE PATHOPHYSIOLOGICAL RESPONSE ! 1 Pathophysiological impart to Vitamin B12 Ingestion and the Clinical Implications of Malabsorption in the Senior Population: A Review of Available Literature Running head: B12 MALABSORPTION IN OLDER ADULTS: THE PATHOPHYSIOLOGICAL RESPONSE ! 2 Introduction The active broker in colored deemed the anti-pernicious anemia factor, was largely inexplicable until 1948, when cobalamin (vitamin B12) was detached by two chemists, Karl A. Folkers (1906-1997) and Alexander R. Todd (1907-1997) (Shampo, Kyle, & Steensma, 2006). It has been much than 60 long time since the disc everywherey of vitamin B12, and researchers have not accurately documented the dependable prevalence of cobalamin inadequacy in the general population. blood serum B12 concentrations in the US population were reported in the field of study wellness and Nutrition Examination Surveys conducted from 1999 to 2002 (Pf eiffer et al., 2007). These surveys showed that the prevalence of B12 deficiency (serum levels little than 148 pmol/L) vary by age, group and number of people affected. It was documented that slight than 3% of the population gray 20 to 39 years, 4% of those aged 40 to 59 years, and around 6% of persons aged 70 years or more(prenominal) were deficient in B12. The study also demonstrated that marginal B12 deficiency (148-221 pmol/L) occurred more commonly in individuals between the ages of 20 to 59 (14% -16%) and over 60 years (20%) of age. The focus of this report is to brushup the kind-hearted pathophysiological response to vitamin B12 ingestion, the clinical implications of vitamin B12 malabsorption in the senior population, and to set send off the clinical manifestations associated with a B12 deficient state. Pathophysiological Response to Vitamin B12 Ingestion Vitamin B12 that is ingested from fauna proteins in food is absorbed and metabolized through a twist complex system that depends on adequate function of! the stomach, intestines and pancreas. The metabolic...If you involve to come up a full essay, order it on our website: BestEssayCheap.com
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